Structure of PDB 4iv2 Chain A Binding Site BS01
Receptor Information
>4iv2 Chain A (length=231) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iv2 Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iv2
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.14 Å
Binding residue
(original residue number in PDB)
I358 V376 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 V72 E76 D221 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iv2
,
PDBe:4iv2
,
PDBj:4iv2
PDBsum
4iv2
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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