Structure of PDB 4iui Chain A Binding Site BS01
Receptor Information
>4iui Chain A (length=211) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYIHRVLDK
ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCS
DLLLEMLDAHR
Ligand information
>4iui Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iui
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I46 L60 V64 E68 E205
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iui
,
PDBe:4iui
,
PDBj:4iui
PDBsum
4iui
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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