Structure of PDB 4iu7 Chain A Binding Site BS01
Receptor Information
>4iu7 Chain A (length=235) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iu7 Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iu7
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.29 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iu7
,
PDBe:4iu7
,
PDBj:4iu7
PDBsum
4iu7
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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