Structure of PDB 4ilm Chain A Binding Site BS01

Receptor Information
>4ilm Chain A (length=279) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPLIFKIGYNVIPLQDVILPTPSSKVLKYLIQSGKLIPSLKDLITSRDKY
KPIFISHLGFNQRRIFQTNKTITKGSRLSSIIAFSTQANVLSEVADEGIF
ETVYGKFHIMIESIEIVEVEKLKEEVEKHMNDNIRVRFVSPTLLSSKVLL
PPSLSERYKKIHAGYSTLPSVGLIVAYAYNVYCNLIGKKEVEVRAFKFGI
LSNALSRIIGYDLHPVTVAIGEDSNLRKARGVMGWIEFDIPDERLKRRAL
NYLLTSSYLGIGRSRGIGFGEIRLEFRKI
Ligand information
Receptor-Ligand Complex Structure
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PDB4ilm Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.
Resolution3.068 Å
Binding residue
(original residue number in PDB)
R47 D48 K49 Y50 K51 S148 K150 V151 L153 S158 H165 G167 Y168 Y180 E195 H217 T220 D226 R232 K233 A234 R235 R268 S269 R270 I272
Binding residue
(residue number reindexed from 1)
R47 D48 K49 Y50 K51 S145 K147 V148 L150 S155 H162 G164 Y165 Y177 E192 H214 T217 D223 R227 K228 A229 R230 R263 S264 R265 I267
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:4ilm, PDBe:4ilm, PDBj:4ilm
PDBsum4ilm
PubMed23454186
UniProtQ97WV8|CAS6B_SACS2 CRISPR-associated endoribonuclease Cas6 2 (Gene Name=cas6b)

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