Structure of PDB 4ii8 Chain A Binding Site BS01

Receptor Information
>4ii8 Chain A (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand ID010
InChIInChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2
InChIKeyWVDDGKGOMKODPV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01
CACTVS 3.370		OCc1ccccc1
OpenEye OEToolkits 1.7.0c1ccc(cc1)CO
FormulaC7 H8 O
Namephenylmethanol
ChEMBLCHEMBL720
DrugBankDB06770
ZINCZINC000000895302
PDB chain4ii8 Chain A Residue 210 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ii8 Characterization of heat induced spherulites of lysozyme reveals new insight on amyloid initiation
Resolution1.88 Å
Binding residue
(original residue number in PDB)		E35 Q57 I58 N59 W63 I98 A107 W108
Binding residue
(residue number reindexed from 1)		E35 Q57 I58 N59 W63 I98 A107 W108
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E35 N46 D48 S50 D52 N59
Catalytic site (residue number reindexed from 1) E35 N46 D48 S50 D52 N59
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ii8, PDBe:4ii8, PDBj:4ii8
PDBsum4ii8
PubMed26926993
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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