Structure of PDB 4igq Chain A Binding Site BS01

Receptor Information
>4igq Chain A (length=273) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKWNPAGARRPVLDEAPVFYPTEEEFEDTLKYIESIRPMAEPYGICRIVP
PSSWKPDKSIWEGSKFSTRVQKVDKLQNRKFGFEPGPEFTLQTFQKYADD
FSKQYFVPSVEDIEGEYWRIVEVPTEEIEVIYGADLETGAQSGWNLNNLP
RLLVPWVYVGMCFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNL
ESAMRKHLPELFEEQPDLLHNLVTQFSPSLLKSEGVHVYRCVQHEGEFVL
TFPRAYHAGFNCGFNCAEAVNVA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4igq Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
D324 W381 Y383 H394 V395 E396 D397 S402 L447 A494 V495 N496
Binding residue
(residue number reindexed from 1)
D135 W156 Y158 H169 V170 E171 D172 S177 L222 A269 V270 N271
Enzymatic activity
Catalytic site (original residue number in PDB) Y383 H394 E396 H482 A494
Catalytic site (residue number reindexed from 1) Y158 H169 E171 H257 A269
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
External links
PDB RCSB:4igq, PDBe:4igq, PDBj:4igq
PDBsum4igq
PubMed23357881
UniProtQ53WJ1|JM703_ORYSJ Lysine-specific demethylase JMJ703 (Gene Name=JMJ703)

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