Structure of PDB 4igo Chain A Binding Site BS01

Receptor Information
>4igo Chain A (length=270) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKWNPAGARRPVLDEAPVFYPTEEEFEDTLKYIESIRPMAEPYGICRIVP
PSSWKPDKSIWEGSKFSTRVQKVDKLQNRKFGFEPGPEFTLQTFQKYADD
FSKQYFVPSVEDIEGEYWRIVEVPTEEIEVIYGADLAQSGWNLNNLPRLL
VPWVYVGMCFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNLESA
MRKHLPELFEEQPDLLHNLVTQFSPSLLKSEGVHVYRCVQHEGEFVLTFP
RAYHAGFNCGFNCAEAVNVA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4igo Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4igo Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H394 E396 H482
Binding residue
(residue number reindexed from 1)		H166 E168 H254
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Y383 H394 E396 H482 A494
Catalytic site (residue number reindexed from 1) Y155 H166 E168 H254 A266
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
External links
PDB RCSB:4igo, PDBe:4igo, PDBj:4igo
PDBsum4igo
PubMed23357881
UniProtQ53WJ1|JM703_ORYSJ Lysine-specific demethylase JMJ703 (Gene Name=JMJ703)

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