Structure of PDB 4i48 Chain A Binding Site BS01

Receptor Information
>4i48 Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDRNTRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQRMYG
CDVGPDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQWRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLKW
Ligand information
>4i48 Chain C (length=9) Species: 82834 (Human immunodeficiency virus type 1 lw12.3 isolate) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TLTSCNTSV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4i48 Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Resolution2.799 Å
Binding residue
(original residue number in PDB)
Y7 Y9 Y59 R62 N63 N66 A69 Q70 T73 D77 Y99 T143 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 Y59 R62 N63 N66 A69 Q70 T73 D77 Y99 T143 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4i48, PDBe:4i48, PDBj:4i48
PDBsum4i48
PubMed23566939
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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