Structure of PDB 4i1p Chain A Binding Site BS01

Receptor Information
>4i1p Chain A (length=379) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLT
EYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSE
NCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIV
FGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMG
KCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELP
ESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPL
DLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFTVC
LSYQYSGLEDTVEDKQEVNVGKPLIAKLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4i1p Activity-Based Probes for Detection of Active MALT1 Paracaspase in Immune Cells and Lymphomas.
Resolution2.403 Å
Binding residue
(original residue number in PDB)		A361 P362 D365 H415 D462 C464 E497 A498 F499 E500 Q502
Binding residue
(residue number reindexed from 1)		A24 P25 D28 H78 D125 C127 E160 A161 F162 E163 Q165
Enzymatic activity
Enzyme Commision number 3.4.22.-
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4i1p, PDBe:4i1p, PDBj:4i1p
PDBsum4i1p
PubMed25556945
UniProtQ9UDY8|MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Gene Name=MALT1)

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