Structure of PDB 4hyk Chain A Binding Site BS01

Receptor Information
>4hyk Chain A (length=336) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYGAVATANYEARKLGVKA
GMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIEVASIDEA
YLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKILAKIIAD
KSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGIQKLRDIL
SKNYNELEKITGKAKALYLLKLAQNKYSEPVENKSKIPHGRYLTLPYNTR
DVKVILPYLKKAINEAYNKVNGIPMRITVIAIMEDLDILSKGKKFKHGIS
IDNAYKVAEDLLRELLVRDKRRNVRRIGVKLDNIII
Ligand information
Receptor-Ligand Complex Structure
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PDB4hyk Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.802 Å
Binding residue
(original residue number in PDB)		G188 V190 L191 R325
Binding residue
(residue number reindexed from 1)		G181 V183 L184 R318
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0042276 error-prone translesion synthesis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hyk, PDBe:4hyk, PDBj:4hyk
PDBsum4hyk
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh)

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