Structure of PDB 4hxj Chain A Binding Site BS01
Receptor Information
>4hxj Chain A (length=59) Species:
9606
(Homo sapiens) [
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STTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYI
PSNYVAPSD
Ligand information
>4hxj Chain C (length=3) Species:
9606
(Homo sapiens) [
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RGT
Receptor-Ligand Complex Structure
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PDB
4hxj
Structural framework of c-Src activation by integrin beta 3
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
E115 D117 W118
Binding residue
(residue number reindexed from 1)
E33 D35 W36
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
Gene Ontology
Biological Process
GO:0006897
endocytosis
GO:0051666
actin cortical patch localization
View graph for
Biological Process
External links
PDB
RCSB:4hxj
,
PDBe:4hxj
,
PDBj:4hxj
PDBsum
4hxj
PubMed
23169783
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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