Structure of PDB 4hrw Chain A Binding Site BS01

Receptor Information
>4hrw Chain A (length=189) Species: 228410 (Nitrosomonas europaea ATCC 19718) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNDALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVRANIAADGGPFAA
AVFERDSGLLIAAGTNRVVPGRCSAAHAAILALSLAQAKLDTHDLSADGL
PACELVTSAEPCVMCFGAVIWSGVRSLVCAARSDDVEAIGFDEGPRPENW
MGGLEARGITVTTGLLRDAACALLREYNACNGVIYNARC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4hrw Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4hrw Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis
Resolution2.43 Å
Binding residue
(original residue number in PDB)		H77 C112 C115
Binding residue
(residue number reindexed from 1)		H77 C112 C115
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0047974 guanosine deaminase activity
Biological Process
GO:0006152 purine nucleoside catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4hrw, PDBe:4hrw, PDBj:4hrw
PDBsum4hrw
PubMed23557066
UniProtQ82Y41

[Back to BioLiP]