Structure of PDB 4hc9 Chain A Binding Site BS01
Receptor Information
>4hc9 Chain A (length=105) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
RECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAA
RRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEG
IQTRN
Ligand information
>4hc9 Chain Y (length=20) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ttcctaaatcagagataacc
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4hc9
DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
P273 N286 L290 R299
Binding residue
(residue number reindexed from 1)
P12 N25 L29 R38
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0008270
zinc ion binding
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
GO:0006357
regulation of transcription by RNA polymerase II
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:4hc9
,
PDBe:4hc9
,
PDBj:4hc9
PDBsum
4hc9
PubMed
23142663
UniProt
P23771
|GATA3_HUMAN Trans-acting T-cell-specific transcription factor GATA-3 (Gene Name=GATA3)
[
Back to BioLiP
]