Structure of PDB 4h8k Chain A Binding Site BS01
Receptor Information
>4h8k Chain A (length=138) Species:
155900
(uncultured organism) [
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KIIIYTDGGARGNPGPAGIGVVITDEKGNTLHESSAYIGETTNNVAEYEA
LIRALEDLQMFGDKLVDMEVEVRMNSELIVRQMQGVYKVKEPTLKEKFAK
IAHIKMERVPNLVFVHIPREKNARADELVNEAIDKALS
Ligand information
>4h8k Chain C (length=14) [
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cgacaccugauucc
..............
Receptor-Ligand Complex Structure
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PDB
4h8k
Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
G11 A12 R13 G14 N15 N45 N77 E79 R121
Binding residue
(residue number reindexed from 1)
G9 A10 R11 G12 N13 N43 N75 E77 R119
Enzymatic activity
Enzyme Commision number
3.1.26.4
: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0004523
RNA-DNA hybrid ribonuclease activity
GO:0016787
hydrolase activity
View graph for
Molecular Function
External links
PDB
RCSB:4h8k
,
PDBe:4h8k
,
PDBj:4h8k
PDBsum
4h8k
PubMed
23500886
UniProt
E0X767
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