Structure of PDB 4h8k Chain A Binding Site BS01

Receptor Information
>4h8k Chain A (length=138) Species: 155900 (uncultured organism) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIIIYTDGGARGNPGPAGIGVVITDEKGNTLHESSAYIGETTNNVAEYEA
LIRALEDLQMFGDKLVDMEVEVRMNSELIVRQMQGVYKVKEPTLKEKFAK
IAHIKMERVPNLVFVHIPREKNARADELVNEAIDKALS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4h8k Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid
Resolution2.3 Å
Binding residue
(original residue number in PDB)
G11 A12 R13 G14 N15 N45 N77 E79 R121
Binding residue
(residue number reindexed from 1)
G9 A10 R11 G12 N13 N43 N75 E77 R119
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4h8k, PDBe:4h8k, PDBj:4h8k
PDBsum4h8k
PubMed23500886
UniProtE0X767

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