Structure of PDB 4gye Chain A Binding Site BS01

Receptor Information
>4gye Chain A (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQITLWKRPIVTIKIGGQLKEALLNTGADDTVLEEVNLPGRWKPKLIGGI
GGFVKVRQYDQVPIEICGHKVIGTVLVGPTPTNVIGRNLMTQIGCTLNF
Ligand information
Receptor-Ligand Complex Structure
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PDB4gye Ligand modifications to reduce the relative resistance of multi-drug resistant HIV-1 protease.
Resolution2.27 Å
Binding residue
(original residue number in PDB)		G27 A28 D29 K45 I47 G48 I50 T82
Binding residue
(residue number reindexed from 1)		G27 A28 D29 K45 I47 G48 I50 T82
Enzymatic activity
Catalytic site (original residue number in PDB) N25 T26 G27
Catalytic site (residue number reindexed from 1) N25 T26 G27
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4gye, PDBe:4gye, PDBj:4gye
PDBsum4gye
PubMed24128815
UniProtQ9QM22

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