Structure of PDB 4ger Chain A Binding Site BS01

Receptor Information

>4ger Chain A (length=304) Species: 1406 (Paenibacillus polymyxa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATGTGKGVLGDTKSFTTTASGSSYQLKDTTRGNGVVTYTASNRQSIPGTI
LTDADNVWNDPAGVDAHTYAAKTYDYYKAKFGRNSIDGRGLQLRSTVHYG
SRYNNAFWNGSQMTYGDGDGSTFIAFSGDPDVVGHELTHGVTEYTSNLEY
YGESGALNEAFSDVIGNDIQRKNWLVGDDIYTPNIAGDALRSMSNPTLYD
QPDHYSNLYTGSSDNGGVHTNSGIINKAYYLLAQGGTFHGVTVNGIGRDA
AVQIYYSAFTNYLTSSSDFSNARAAVIQAAKDQYGANSAEATAAAKSFDA
VGVN

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

4ger Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4ger Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa.
Resolution	1.59 Å
Binding residue (original residue number in PDB)	H135 H139 E159
Binding residue (residue number reindexed from 1)	H135 H139 E159
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H135 E136 H139 Y150 E159 D214 H219
Catalytic site (residue number reindexed from 1)	H135 E136 H139 Y150 E159 D214 H219
Enzyme Commision number	3.4.24.28: bacillolysin.

Gene Ontology

	Molecular Function
GO:0004222	metalloendopeptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:4ger, PDBe:4ger, PDBj:4ger
PDBsum	4ger
PubMed	23275160
UniProt	P29148\|NPRE_PAEPO Bacillolysin (Gene Name=npr)

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