Structure of PDB 4fx4 Chain A Binding Site BS01

Receptor Information
>4fx4 Chain A (length=128) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ECACYTTRRAARQLGQAYDRALRPSGLTNTQFSTLAVISLSEGSDLTMSE
LAARIGVERTTLTRNLEVMRRDGLVRVMAGCKRIELTAKGRAALQKAVPL
WRGVQAEVTAWPRVRRDIANLGQAAEAC
Ligand information
Receptor-Ligand Complex Structure
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PDB4fx4 The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis.
Resolution3.1001 Å
Binding residue
(original residue number in PDB)
R16 R20 Q24 M59 S60 R70 T74 R75 C96 K97
Binding residue
(residue number reindexed from 1)
R8 R12 Q16 M48 S49 R59 T63 R64 C81 K82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006950 response to stress
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4fx4, PDBe:4fx4, PDBj:4fx4
PDBsum4fx4
PubMed22992749
UniProtO53397

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