Structure of PDB 4fvd Chain A Binding Site BS01

Receptor Information
>4fvd Chain A (length=138) Species: 39054 (Enterovirus A71) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGAIYVGNFRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARC
NCQTGVYYCNSRRKHYPVSFSKPSLIYVEASEYYPARYQSHLMLAQGHSE
PGDAGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4fvd Conformational Plasticity of 2A Proteinase from Enterovirus 71
Resolution1.66 Å
Binding residue
(original residue number in PDB)		H21 D39 Y89 Y90 R93 Q95 P107 G108 A110 S125 T126
Binding residue
(residue number reindexed from 1)		H15 D33 Y83 Y84 R87 Q89 P101 G102 A104 S119 T120
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4fvd, PDBe:4fvd, PDBj:4fvd
PDBsum4fvd
PubMed23616646
UniProtA9XG43

[Back to BioLiP]