Structure of PDB 4ftv Chain A Binding Site BS01

Receptor Information
>4ftv Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>4ftv Chain C (length=9) Species: 39015 (Human T-cell lymphotropic virus type 1 (african isolate)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ftv Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
Resolution2.74 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4ftv, PDBe:4ftv, PDBj:4ftv
PDBsum4ftv
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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