Structure of PDB 4ftb Chain A Binding Site BS01

Receptor Information
>4ftb Chain A (length=321) Species: 12287 (Flock House virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQTAPVPQQNVPRLTRLSQPGLAFLKCAFAPPDFNTDPGKGIPDRFEGKV
VSRKDVLNQSISFTAGQDTFILIAPTPGVAYWSASVPAGTFPTSATTFNP
VNYPGFTSMFGTTSTSRSDQVSSFRYASMNVGIYPTSNLMQFAGSITVWK
CPVKLSTVQFPVATDPATSSLVHTLVGLDGVLAVGPDNFSESFIKGVFSQ
SACNEPDFEFNDILEGIQTLPPANVSLGSTGQPFTMDSGAEATSGVVGWG
NMDTIVIRVSAPEGAVNSAILKAWSCIEYRPNPNAMLYQFGHDSPPLDEV
ALQEYRTVARSLPVAVIAAQN
Ligand information
>4ftb Chain D (length=21) Species: 12287 (Flock House virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ASMWERVKSIIKSSLAAASNI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ftb Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
Resolution2.7 Å
Binding residue
(original residue number in PDB)		K68 F71 D75 F76 F240 E346 S353 Q362
Binding residue
(residue number reindexed from 1)		K26 F29 D33 F34 F198 E304 S311 Q320
Enzymatic activity
Enzyme Commision number 3.4.23.44: nodavirus endopeptidase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4ftb, PDBe:4ftb, PDBj:4ftb
PDBsum4ftb
PubMed
UniProtP12870|CAPSD_FHV Capsid protein alpha (Gene Name=alpha)

[Back to BioLiP]