Structure of PDB 4flz Chain A Binding Site BS01

Receptor Information
>4flz Chain A (length=754) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGMIIDADYITEDGKPIIRIFKKEKGEFKVEYDRTFRPYIYALLKDDSAI
DEVKKITAERHGKIVRITEVEKVQKKFLGRPIEVWKLYLEHPQDVPAIRE
KIREHPAVVDIFEYDIPFAKRYLIDKGLTPMEGNEELTFLAVDIETLYHE
GEEFGKGPIIMISYADEEGAKVITWKSIDLPYVEVVSSEREMIKRLVKVI
REKDPDVIITYNGDNFAFPYLLKRAEKLGIKLPLGRDNSEPKMQRMGDSL
AVEIKGRIHFDLFPVIRRTINLPTYTLEAVYEAIFGKSKEKVYAHEIAEA
WETGKGLERVAKYSMEDAKVTFELGKEFFPMEAQLARLVGQPVWDVSRSS
TGNLVEWFLLRKAYERNELAPNKPDEREYERRLRESYKEPEKGLWEGIVS
LDFRSLYPSIIITHNVSPDTLNRENCKEYDVAPQVGHRFCKDFPGFIPSL
LGNLLEERQKIKKRMKESKDPVEKKLLDYRQRAIKILANSYYGYYGYAKA
RWYCKECAESVTAWGRQYIDLVRRELESRGFKVLYIDTDGLYATIPGAKH
EEIKEKALKFVEYINSKLPGLLELEYEGFYARGFFVTKKKYALIDEEGKI
VTRGLEIVRRDWSEIAKETQAKVLEAILKHGNVDEAVKIVKEVTEKLSKY
EIPPEKLVIYEQITRPLSEYKAIGPHVAVAKRLAAKGVKVKPGMVIGYIV
LRGDGPISKRAIAIEEFDPKKHKYDAEYYIENQVLPAVERILRAFGYRKE
DLKY
Ligand information
Receptor-Ligand Complex Structure
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PDB4flz Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R265 R612 R613 D614 E664 Q665 T667 R668 Y673 K674 H679
Binding residue
(residue number reindexed from 1)		R267 R609 R610 D611 E661 Q662 T664 R665 Y670 K671 H676
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4flz, PDBe:4flz, PDBj:4flz
PDBsum4flz
PubMed22902479
UniProtP0CL77|DPOL_PYRAB DNA polymerase 1 (Gene Name=polI)

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