Structure of PDB 4fgn Chain A Binding Site BS01
Receptor Information
>4fgn Chain A (length=126) [
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EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVT
FISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLM
YSALTRDPFSVIEESLPGGLKEHDFN
Ligand information
>4fgn Chain Z (length=23) [
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aggcctccaaaaaagcctcctca
Receptor-Ligand Complex Structure
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PDB
4fgn
Analysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral Assembly.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
N153 T155 R202 H203 R204 A207 N210
Binding residue
(residue number reindexed from 1)
N21 T23 R70 H71 R72 A75 N78
Binding affinity
PDBbind-CN
: Kd~12.3nM
Enzymatic activity
Enzyme Commision number
3.6.4.-
Gene Ontology
Molecular Function
GO:0003688
DNA replication origin binding
Biological Process
GO:0006260
DNA replication
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Molecular Function
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Biological Process
External links
PDB
RCSB:4fgn
,
PDBe:4fgn
,
PDBj:4fgn
PDBsum
4fgn
PubMed
23269808
UniProt
P03070
|LT_SV40 Large T antigen
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