Structure of PDB 4fgn Chain A Binding Site BS01

Receptor Information
>4fgn Chain A (length=126) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVT
FISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLM
YSALTRDPFSVIEESLPGGLKEHDFN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4fgn Analysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral Assembly.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
N153 T155 R202 H203 R204 A207 N210
Binding residue
(residue number reindexed from 1)
N21 T23 R70 H71 R72 A75 N78
Binding affinityPDBbind-CN: Kd~12.3nM
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003688 DNA replication origin binding
Biological Process
GO:0006260 DNA replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4fgn, PDBe:4fgn, PDBj:4fgn
PDBsum4fgn
PubMed23269808
UniProtP03070|LT_SV40 Large T antigen

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