Structure of PDB 4fb3 Chain A Binding Site BS01

Receptor Information
>4fb3 Chain A (length=115) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCL
VHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVV
TAAPFQLITENKPGL
Ligand information
Receptor-Ligand Complex Structure
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PDB4fb3 Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner.
Resolution3.79 Å
Binding residue
(original residue number in PDB)		N307 T309 K355 H356 R357 A360
Binding residue
(residue number reindexed from 1)		N18 T20 K66 H67 R68 A71
Binding affinityPDBbind-CN: Kd=38nM
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003688 DNA replication origin binding
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:4fb3, PDBe:4fb3, PDBj:4fb3
PDBsum4fb3
PubMed24109229
UniProtP0DOJ4|LT_POVBG Large T antigen

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