Structure of PDB 4f50 Chain A Binding Site BS01

Receptor Information
>4f50 Chain A (length=337) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSSGAVATANYEARKLGV
KAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIEVASID
EAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKILAKII
ADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGIQKLRD
ILSKNYNELEKITGKAKALYLLKLAQNKYSEPVENKSKIPHGRIVTMKRN
SRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPH
GISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4f50 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.215 Å
Binding residue
(original residue number in PDB)		A57 G58 P185 G186 G188 S189 V190 L191 K322
Binding residue
(residue number reindexed from 1)		A52 G53 P180 G181 G183 S184 V185 L186 K317
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4f50, PDBe:4f50, PDBj:4f50
PDBsum4f50
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

[Back to BioLiP]