Structure of PDB 4f4y Chain A Binding Site BS01

Receptor Information
>4f4y Chain A (length=343) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSGRTKTSGAVATANYEA
RKLGVKAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIE
VASIDEAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKI
LAKIIADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGI
QKLRDILSKNYNELEKITGKAKALYLLKLAQDEYNEPIRTRVRKSIGRYL
TLPYNTRDVKVILPYLKKAINEAYNKVNGIPMRITVIAIMEDLDILSKGK
KFKHGISIDNAYKVAEDLLRELLVRDKRRNVRRIGVKLDNIII
Ligand information
Receptor-Ligand Complex Structure
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PDB4f4y Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.338 Å
Binding residue
(original residue number in PDB)		S103 D105 E106 G186 G188 Y225 R241 S297 K298 K301 K303 R325
Binding residue
(residue number reindexed from 1)		S103 D105 E106 G186 G188 Y225 R241 S297 K298 K301 K303 R325
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f4y, PDBe:4f4y, PDBj:4f4y
PDBsum4f4y
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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