Structure of PDB 4f1n Chain A Binding Site BS01

Receptor Information
>4f1n Chain A (length=904) Species: 436907 (Vanderwaltozyma polyspora DSM 70294) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTHAIYKVENRHDYGTKGTKVDILTNHILLAVGNDVPTEKIDKELVPKLD
GWWKTAFIFTYHIDFKLSKPKKYELIEALLDEDEILYKYRDRIAFNGEDT
IYSHVPLEEFTLFDGCWEEMVSQITLKFSGKVGLKDIYNDTTTQDTEVQE
SRMSAIDKTCLLSLLGAKFMSTDDLIFQVQGNKFFIFNNFAKAIPFQIGG
YLLQGFTVSLTHVYGGVALNTVSVPAPFIKHTKYLPGDPRFKNNEKEQFT
LMDWIIECYHQSKAIRDIRYNPKTAPPPSVKDLNYFVEKNTDISALLKGL
KVYRPYINRSSKGIVGFTRESAVSMRNTIDYFKRKYDITLKYPDMKLVNL
GGKNDVVPPECLTIVPGQKLKGQIFDTKTYIDFSAIRPTEKFDLISRLSM
PAIKRGLTDSENSAYQFMRVPSRILDAPVVQFKESTFEYKDKSYGTKHEE
SKGNWNMKGHQFISTPAKQVNLRAIFINNANTAPPASMESELDISMDKFA
SDVKQLGVDFNVSGKPILINQFGPPIKPTFETSPGEISLLNLLENIPSNT
YILYVLRRGNDSAVYDRLKYITDLKFGALNSCVVWDNFKKNSIQYNSNVV
MKMNLKLLGSNHSLSIENNKLLIDKESNLPILVLGSDVTHYPEKDQNSIA
SLVGSYDDKFTQFPGDYMLQDGPGEEIITNVGSLMLNRLKIYQKHNNGKL
PTKIMYFRDGVSVDQFSQVVKIEVKSIKESVRKFGPQLNGGNKYDPPVTC
IATVKRNQVRFIPIQENAKNEKGEEVAVQSMGNVMPGTVVDRGITSVAHF
DFFIQSHQALKGTGVPCHYWCLYDENQSTSDYLQEICNNLCYIFGRSTTS
VKVPAPVYYADLLCTRATCFFKAGFELNMAQATVSKNVLLPQVNDNIKSV
MYYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4f1n Structure of yeast Argonaute with guide RNA.
Resolution3.187 Å
Binding residue
(original residue number in PDB)
Q444 Y681 I682 S685 A686 Y902 K906 C919 V921 N924 Y932 N935 V936 K939 R1093 H1144 L1147 K1148 G1151 V1152 F1181 R1183 S1184 T1186 V1188 K1189 Y1195
Binding residue
(residue number reindexed from 1)
Q180 Y380 I381 S384 A385 Y565 K569 C582 V584 N587 Y595 N598 V599 K602 R756 H807 L810 K811 G814 V815 F844 R846 S847 T849 V851 K852 Y858
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4f1n, PDBe:4f1n, PDBj:4f1n
PDBsum4f1n
PubMed22722195
UniProtA7TMA9

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