Structure of PDB 4ewt Chain A Binding Site BS01

Receptor Information

>4ewt Chain A (length=389) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MNQQLIETLKSKEGKMIEIRRYLHQHPELSFHEDETAKYIAEFYKGKDVE
VETNVGPRGIKVTIDSGKPGKTLAIRADFDALPITEDTGLSFASQNKGVM
HACGHDAHTAYMLVLAETLAEMKDSFTGKVVVIHQPAEEVPPGGAKTMIE
NGVLDGVDHVLGVHVMSTMKTGKVYYRPGYVQTGRAFFKLKVQGKGGHGS
SPHMANDAIVAGSYFVTALQTVVSRRLSPFETGVVTIGSFDGKGQFNVIK
DVVEIEGDVRGLTDATKATIEKEIKRLSKGLEDMYGVTCTLEYNDDYPAL
YNDPEFTEYVAKTLKEANLDFGVEMCEPQPPSEDFAYYAKERPSAFIYTG
AAVENGEIYPHHHPKFNISEKSLLISAEAVGTVVLDYLK

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

4ewt Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4ewt Structure of an amidohydrolase, SACOL0085, from methicillin-resistant Staphylococcus aureus COL
Resolution	2.1 Å
Binding residue (original residue number in PDB)	C103 E139 H362
Binding residue (residue number reindexed from 1)	C103 E139 H362
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.5.1.14: N-acyl-aliphatic-L-amino acid amidohydrolase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:4ewt, PDBe:4ewt, PDBj:4ewt
PDBsum	4ewt
PubMed	23385746
UniProt	A0A0H2WZV8

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