Structure of PDB 4ev6 Chain A Binding Site BS01

Receptor Information
>4ev6 Chain A (length=315) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVIAIAKDGSIVEPKLDEISFEDYRLIWIDCYDPKDEELYKLSKKIGISV
SDLQIGLDEQEIPRVEEDEDFYLIIYKAPLFEEDITTTSLGIYIKNNLLL
TIHSDKIKAIGRLHKLISTKKPRIVFERGIGFLLYHILNEITRSYSRILM
NLEDELEELEDKLLAGYDREVMEKILGLRKTLVYFHKSLIANRDVLVLLK
RKYLPITTKEDRENFEDLYYDTLQLIDMSATYREVLTSMMDITLSLENIK
MNQIMKILTMVTTIFAVPMWITGIYGMNFSYLPLANNPQGFWLVMALMVV
IIMIFVYIFRRSGWI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4ev6 Chain A Residue 409 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ev6 Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA
Resolution3.2 Å
Binding residue
(original residue number in PDB)		E71 D72
Binding residue
(residue number reindexed from 1)		E69 D70
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0015087 cobalt ion transmembrane transporter activity
GO:0015095 magnesium ion transmembrane transporter activity
GO:0042802 identical protein binding
GO:0046873 metal ion transmembrane transporter activity
GO:0050897 cobalt ion binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006824 cobalt ion transport
GO:0015693 magnesium ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
GO:1903830 magnesium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4ev6, PDBe:4ev6, PDBj:4ev6
PDBsum4ev6
PubMed23091000
UniProtQ58439|CORA_METJA Cobalt/magnesium transport protein CorA (Gene Name=corA)

[Back to BioLiP]