Structure of PDB 4dwa Chain A Binding Site BS01

Receptor Information

>4dwa Chain A (length=154) Species: 268305 (Bovine viral diarrhea virus 1-CP7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ENITQWNLQDNGTEGIQRAMFQRGVNRSLKGIWPEKICTGVPSHLATDTE
LKAIHGMMDASEKTNYTCCRLQRHEWNKHGWCNWYNIEPWILLMNKTQAN
LTEGRECAVTCRYDRDSDLNVVTQARDSPTPLTGCKKGKNFSFAGILVQG
PCNF

Ligand information

>4dwa Chain D (length=3) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cuc

...

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4dwa Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Resolution	3.01 Å
Binding residue (original residue number in PDB)	N9 K32 A62 R72
Binding residue (residue number reindexed from 1)	N7 K30 A60 R70

Enzymatic activity

Enzyme Commision number

2.7.7.48: RNA-directed RNA polymerase.
3.4.21.113: pestivirus NS3 polyprotein peptidase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
4.6.1.19: ribonuclease T2.

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0033897	ribonuclease T2 activity

View graph for
Molecular Function

External links

PDB	RCSB:4dwa, PDBe:4dwa, PDBj:4dwa
PDBsum	4dwa
PubMed	22579253
UniProt	Q96662\|POLG_BVDVC Genome polyprotein

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