Structure of PDB 4dmb Chain A Binding Site BS01

Receptor Information
>4dmb Chain A (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKD
DRLNKDRCVRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQL
LPEDLRKELYELWEEYETQSSAEAKFVKQLDQCEMILQASEYEDLEHKPG
RLQDFYDSTAGKFNHPEIVQLVSELEAERSTNIAAAAS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4dmb Chain A Residue 306 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4dmb Northeast Structural Genomics Consortium Target HR6723
Resolution1.9 Å
Binding residue
(original residue number in PDB)		H49 H77 D78 D143
Binding residue
(residue number reindexed from 1)		H37 H65 D66 D131
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.89: 5'-deoxynucleotidase.
Gene Ontology
Molecular Function
GO:0002953 5'-deoxynucleotidase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4dmb, PDBe:4dmb, PDBj:4dmb
PDBsum4dmb
PubMed
UniProtQ7Z4H3|HDDC2_HUMAN 5'-deoxynucleotidase HDDC2 (Gene Name=HDDC2)

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