Structure of PDB 4dkj Chain A Binding Site BS01

Receptor Information
>4dkj Chain A (length=388) Species: 272633 (Malacoplasma penetrans HF-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKIKVIKVFEAFAGIGSQFKALKNIARSKNWEIQHSGMVEWFVDAIVSYV
AIHSKNFNPKIERLDRDILSISNDSKMPISEYGIKKINNTIKASYLNYAK
KHFNNLFDIKKVNKDNFPKNIDIFTYSFPCQDLSVQGLQKGIDKELNTRS
GLLWEIERILEEIKNSFSKEEMPKYLLMENVKNLLSHKNKKNYNTWLKQL
EKFGYKSKTYLLNSKNFDNCQNRERVFCLSIRDDYLEKTGFKFKELEKVK
NPPKKIKDILVDSSNYKYLNLNKYETTTFRETKSNIISRPLKNYTTFNSE
NYVYNINGIGPTLTASGANSRIKIETQQGVRYLTPLECFKYMQFDVNDFK
KVQSTNLISENKMIYIAGNSIPVKILEAIFNTLEFVNN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4dkj CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		F133 P134 C135 Q136 S139 V140 Q141 G142 L143 E184 R230 T287 S289 F302 N303 P316 T317 T319 A320 S321 G322 N324 G373
Binding residue
(residue number reindexed from 1)		F128 P129 C130 Q131 S134 V135 Q136 G137 L138 E179 R225 T282 S284 F297 N298 P311 T312 T314 A315 S316 G317 N319 G368
Enzymatic activity
Catalytic site (original residue number in PDB) C135 E184 R228 R230
Catalytic site (residue number reindexed from 1) C130 E179 R223 R225
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4dkj, PDBe:4dkj, PDBj:4dkj
PDBsum4dkj
PubMed23248272
UniProtQ8EVR5

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