Structure of PDB 4dfw Chain A Binding Site BS01
Receptor Information
>4dfw Chain A (length=219) Species:
9606
(Homo sapiens) [
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HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSPNSLMK
KITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILH
LSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCK
ELASRLRYARTMVDKLLSS
Ligand information
>4dfw Chain D (length=5) [
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PLHST
Receptor-Ligand Complex Structure
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PDB
4dfw
Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides
Resolution
1.55 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 Y417 Y481 Y485 L490 L491 H538 K540
Binding residue
(residue number reindexed from 1)
W42 V43 D44 Y45 Y107 Y111 L116 L117 H164 K166
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:4dfw
,
PDBe:4dfw
,
PDBj:4dfw
PDBsum
4dfw
PubMed
22292814
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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