Structure of PDB 4dcb Chain A Binding Site BS01

Receptor Information
>4dcb Chain A (length=277) Species: 632 (Yersinia pestis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIPNISPDSFTVAASTGMLSGKSHEMLYDAETGRKISQLDWKIKNVAILK
GDISWDPYSFLTLNARGWTSLASGSGNMDNYDWMNENQSEWTDHSSHPAT
NVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFSWTATGGSYSYNNGA
YTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRAHD
NDEHYMRDLTFREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGK
GGTQTIDAAGISNKNYTVTAGLQYRFG
Ligand information
Receptor-Ligand Complex Structure
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PDB4dcb Structural basis for activation of an integral membrane protease by lipopolysaccharide.
Resolution2.033 Å
Binding residue
(original residue number in PDB)		N84 D86 M88 D97 Y150 V165 H208 R211
Binding residue
(residue number reindexed from 1)		N80 D82 M84 D93 Y146 V161 H204 R207
Enzymatic activity
Catalytic site (original residue number in PDB) N84 D86 S99 D206 H208
Catalytic site (residue number reindexed from 1) N80 D82 S95 D202 H204
Enzyme Commision number 3.4.23.48: plasminogen activator Pla.
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0009279 cell outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4dcb, PDBe:4dcb, PDBj:4dcb
PDBsum4dcb
PubMed22645135
UniProtP17811|PLA_YERPE Plasminogen activator (Gene Name=pla)

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