Structure of PDB 4d6u Chain A Binding Site BS01

Receptor Information
>4d6u Chain A (length=444) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEK
NNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKA
LSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFN
YLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAG
GLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPLA
HVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATN
KLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSATE
SEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAE
VDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWLR
Ligand information
>4d6u Chain I (length=27) Species: 9913 (Bos taurus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LCRESLRGQAAGLVASVSLNVPASVRY
Receptor-Ligand Complex Structure
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PDB4d6u Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1.
Resolution4.09 Å
Binding residue
(original residue number in PDB)		E140 Y284
Binding residue
(residue number reindexed from 1)		E139 Y283
Enzymatic activity
Catalytic site (original residue number in PDB) Y57 E60 H61 E130 E137
Catalytic site (residue number reindexed from 1) Y56 E59 H60 E129 E136
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4d6u, PDBe:4d6u, PDBj:4d6u
PDBsum4d6u
PubMed25564664
UniProtP31800|QCR1_BOVIN Cytochrome b-c1 complex subunit 1, mitochondrial (Gene Name=UQCRC1)

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