Structure of PDB 4csj Chain A Binding Site BS01
Receptor Information
>4csj Chain A (length=247) Species:
9606
(Homo sapiens) [
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PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAK
AIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLII
NEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDG
LKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVV
ENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>4csj Chain B (length=13) Species:
9606
(Homo sapiens) [
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ENALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
4csj
The Discovery of Potent and Selective Non-Steroidal Glucocorticoid Receptor Modulators, Suitable for Inhalation.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
V575 K579 R585 L589 M593 Q597 E751 M752 E755 N759
Binding residue
(residue number reindexed from 1)
V46 K50 R56 L60 M64 Q68 E222 M223 E226 N230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4csj
,
PDBe:4csj
,
PDBj:4csj
PDBsum
4csj
PubMed
24755427
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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