Structure of PDB 4cls Chain A Binding Site BS01
Receptor Information
>4cls Chain A (length=459) Species:
9606
(Homo sapiens) [
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MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISG
FTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDA
LLALWRVERKQLKNIITVVIKCSLEIHGLFETIRVKIGLAAGHISMLVFG
DETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVP
DQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPD
PELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAE
EIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDE
LTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIG
QKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGP
LYQYWGRTE
Ligand information
Ligand ID
MG
InChI
InChI=1S/Mg/q+2
InChIKey
JLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341
[Mg++]
Formula
Mg
Name
MAGNESIUM ION
ChEMBL
DrugBank
DB01378
ZINC
PDB chain
4cls Chain A Residue 1468 [
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Receptor-Ligand Complex Structure
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PDB
4cls
Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Resolution
1.85 Å
Binding residue
(original residue number in PDB)
D47 D99
Binding residue
(residue number reindexed from 1)
D47 D99
Annotation score
1
Enzymatic activity
Enzyme Commision number
4.6.1.1
: adenylate cyclase.
Gene Ontology
Biological Process
GO:0009190
cyclic nucleotide biosynthetic process
GO:0035556
intracellular signal transduction
View graph for
Biological Process
External links
PDB
RCSB:4cls
,
PDBe:4cls
,
PDBj:4cls
PDBsum
4cls
PubMed
24567411
UniProt
Q96PN6
|ADCYA_HUMAN Adenylate cyclase type 10 (Gene Name=ADCY10)
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