Structure of PDB 4chu Chain A Binding Site BS01

Receptor Information
>4chu Chain A (length=126) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRL
RKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDKSLTHALWRDL
SDRLTGFLNNITLGELVNNQEVLDVS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4chu The Unique Regulation of Iron-Sulfur Cluster Biogenesis in a Gram-Positive Bacterium.
Resolution2.489 Å
Binding residue
(original residue number in PDB)		R2 S5 K6 Y9 S38 S40 Y41 Q44 R59 G60 P61
Binding residue
(residue number reindexed from 1)		R3 S6 K7 Y10 S39 S41 Y42 Q45 R60 G61 P62
Binding affinityPDBbind-CN: Kd=180nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005506 iron ion binding
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4chu, PDBe:4chu, PDBj:4chu
PDBsum4chu
PubMed24847070
UniProtC3SZN7

[Back to BioLiP]