Structure of PDB 4c5h Chain A Binding Site BS01

Receptor Information
>4c5h Chain A (length=429) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSYDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTSFWVA
TILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPR
TIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLNLECVDK
DRISQVRLATVTKIVGKRLFLRYFDSDDGFWCHEDSPIIHPVGWATTVGH
NLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTNSF
VEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCY
HEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLF
HRIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEY
DQWLDCESADIYPVGWCVLVNHKLEGPPR
Ligand information
>4c5h Chain B (length=26) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SRRWEQKLVHIKTMEGEFSVTMWASG
Receptor-Ligand Complex Structure
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PDB4c5h Structural Basis for Targeting the Chromatin Repressor Sfmbt to Polycomb Response Elements
Resolution3.2 Å
Binding residue
(original residue number in PDB)
N566 V634 G635 A638 P643 L644 V662 L665 A668 R669 T670
Binding residue
(residue number reindexed from 1)
N33 V86 G87 A90 P95 L96 V114 L117 A120 R121 T122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:4c5h, PDBe:4c5h, PDBj:4c5h
PDBsum4c5h
PubMed24186981
UniProtQ9VK33|SMBT_DROME Polycomb protein Sfmbt (Gene Name=Sfmbt)

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