Structure of PDB 4c2g Chain A Binding Site BS01

Receptor Information
>4c2g Chain A (length=433) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYM
DKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPND
EIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRA
EIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGL
VIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKK
AYPVNVITDKGSAAASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGD
GSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVD
MNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVI
DTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF
Ligand information
Receptor-Ligand Complex Structure
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PDB4c2g Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
G255 L257 A309 A310 K334 V337 Q338 F478
Binding residue
(residue number reindexed from 1)
G210 L212 A264 A265 K289 V292 Q293 F433
Enzymatic activity
Enzyme Commision number 3.4.21.102: C-terminal processing peptidase.
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0042277 peptide binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0007165 signal transduction
GO:0030435 sporulation resulting in formation of a cellular spore
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4c2g, PDBe:4c2g, PDBj:4c2g
PDBsum4c2g
PubMed24243021
UniProtO35002|CTPB_BACSU Carboxy-terminal processing protease CtpB (Gene Name=ctpB)

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