Structure of PDB 4byg Chain A Binding Site BS01

Receptor Information
>4byg Chain A (length=663) Species: 272624 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSPEYLDMRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLAT
PVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAWIYSMVAVLWPGVF
PHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLV
PESAHRIKEDGSEEEVSLDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDE
SMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQMVS
DAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIA
AVSVLIIACPCALGLATPMSIMVGVGKGAQSGVLIKNAEALERMEKVNTL
VVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHA
AKEKGLSLGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLF
EKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTPETILELQQSGIEI
VMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAG
DGVNDAPALAKADIGIAMGTGTDVAIESAGVTLLHGDLRGIAKARRLSES
TMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALSSVS
VIINALRLKRVTL
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain4byg Chain A Residue 995 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4byg Dephosphorylation of Pib-Type Cu(I)-Atpases as Studied by Metallofluoride Complexes
Resolution2.85 Å
Binding residue
(original residue number in PDB)		D426 K427 T428 T577
Binding residue
(residue number reindexed from 1)		D353 K354 T355 T504
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D426 D624 D628
Catalytic site (residue number reindexed from 1) D353 D551 D555
Enzyme Commision number 7.2.2.8: P-type Cu(+) transporter.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0005215 transporter activity
GO:0005507 copper ion binding
GO:0005524 ATP binding
GO:0015662 P-type ion transporter activity
GO:0016887 ATP hydrolysis activity
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity
GO:0043682 P-type divalent copper transporter activity
GO:0046872 metal ion binding
GO:0140581 P-type monovalent copper transporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0006825 copper ion transport
GO:0006878 intracellular copper ion homeostasis
GO:0055070 copper ion homeostasis
GO:0060003 copper ion export
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4byg, PDBe:4byg, PDBj:4byg
PDBsum4byg
PubMed
UniProtQ5ZWR1|COPA_LEGPH Copper-exporting P-type ATPase (Gene Name=copA)

[Back to BioLiP]