Structure of PDB 4bxo Chain A Binding Site BS01

Receptor Information
>4bxo Chain A (length=202) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRS
QSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDRRRTKSYDSLLTTLIG
AGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPKSEALQFYLSIPNIS
YITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQ
ML
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4bxo Chain A Residue 2050 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bxo Architecture and DNA Recognition Elements of the Fanconi Anemia Fancm-Faap24 Complex.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D1854 E1864 R1865
Binding residue
(residue number reindexed from 1)		D37 E47 R48
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4bxo, PDBe:4bxo, PDBj:4bxo
PDBsum4bxo
PubMed23932590
UniProtQ8IYD8|FANCM_HUMAN Fanconi anemia group M protein (Gene Name=FANCM)

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