Structure of PDB 4buo Chain A Binding Site BS01

Receptor Information
>4buo Chain A (length=304) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDY
YLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTY
ATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPM
LFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVAS
ILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLM
FCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQVF
LSTL
Ligand information
Receptor-Ligand Complex Structure
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PDB4buo Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Resolution2.75 Å
Binding residue
(original residue number in PDB)		D54 L55 D56 F128 H132 Y146 V224 T226 R327 F331 C332 I334 W339 F344 Y347
Binding residue
(residue number reindexed from 1)		D3 L4 D5 F74 H78 Y92 V170 T172 R247 F251 C252 I254 W259 F264 Y267
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4buo, PDBe:4buo, PDBj:4buo
PDBsum4buo
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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