Structure of PDB 4bpl Chain A Binding Site BS01

Receptor Information
>4bpl Chain A (length=422) Species: 4530 (Oryza sativa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQ
FLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSD
DVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNAT
WTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDG
TNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCI
IDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIG
PLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLI
CPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIEN
LQSHDNNEIYEKAVKILEAYWM
Ligand information
Receptor-Ligand Complex Structure
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PDB4bpl Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha
Resolution2.3 Å
Binding residue
(original residue number in PDB)		S101 E103 W138 N142 A144 S145 G146 T151 Q177 W180 N184 G187 D188 W223 N227 R230 W264 Y268 R306 V312 T313 G314 W349 N353 A356 E388 W391 N395 S398
Binding residue
(residue number reindexed from 1)		S29 E31 W66 N70 A72 S73 G74 T79 Q105 W108 N112 G115 D116 W151 N155 R158 W192 Y196 R234 V240 T241 G242 W277 N281 A284 E316 W319 N323 S326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bpl, PDBe:4bpl, PDBj:4bpl
PDBsum4bpl
PubMed24503158
UniProtQ71VM4|IMA1A_ORYSJ Importin subunit alpha-1a (Gene Name=Os01g0253300)

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