Structure of PDB 4bpj Chain A Binding Site BS01

Receptor Information
>4bpj Chain A (length=144) Species: 9606,10090 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDDLYRQSLEIISRYLREQATGSKGAAGRRALETLRRVGDGVQRNHETAF
QGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHL
KTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bpj Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Resolution1.599 Å
Binding residue
(original residue number in PDB)		H224 F228 M231 L235 V249 V253 D256 N260 G262 R263 T266 F318 F319
Binding residue
(residue number reindexed from 1)		H46 F50 M53 L57 V71 V75 D78 N82 G84 R85 T88 F140 F141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:4bpj, PDBe:4bpj, PDBj:4bpj
PDBsum4bpj
PubMed23929624
UniProtP97287|MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Gene Name=Mcl1);
Q07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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