Structure of PDB 4bnc Chain A Binding Site BS01

Receptor Information
>4bnc Chain A (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPA
MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFSD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4bnc Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		R391 R394 Y397 K404 R409 Y410
Binding residue
(residue number reindexed from 1)		R58 R61 Y64 K71 R76 Y77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4bnc, PDBe:4bnc, PDBj:4bnc
PDBsum4bnc
PubMed25866208
UniProtP50549|ETV1_HUMAN ETS translocation variant 1 (Gene Name=ETV1)

[Back to BioLiP]