Structure of PDB 4bfi Chain A Binding Site BS01

Receptor Information
>4bfi Chain A (length=191) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLTQVNTTVSVQIGTKALLCCFSIPLTKAVLITWIIKLRGLPSCTIAYKV
DTKTNETSCLGRNITWASTPDHSPELQISAVTLQHEGTYTCETVTPEGNF
EKNYDLQVLVPPEVTYFPEKNRSAVCEAMAGKPAAQISWSPDGDCVTTSE
SHSNGTVTVRSTCHWEQNNVSDVSCIVSHLTGNQSLSIELG
Ligand information
Ligand IDCYS
InChIInChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyXUJNEKJLAYXESH-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)S
CACTVS 3.341N[C@@H](CS)C(O)=O
ACDLabs 10.04O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)S
FormulaC3 H7 N O2 S
NameCYSTEINE
ChEMBLCHEMBL863
DrugBankDB00151
ZINCZINC000000895042
PDB chain4bfi Chain A Residue 1207 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4bfi Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution
Resolution3.22 Å
Binding residue
(original residue number in PDB)		C34 E89
Binding residue
(residue number reindexed from 1)		C20 E75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0038023 signaling receptor activity
Biological Process
GO:0150077 regulation of neuroinflammatory response

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Molecular Function
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Biological Process
External links
PDB RCSB:4bfi, PDBe:4bfi, PDBj:4bfi
PDBsum4bfi
PubMed23602662
UniProtQ9ES57|MO2R1_MOUSE Cell surface glycoprotein CD200 receptor 1 (Gene Name=Cd200r1)

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