Structure of PDB 4ayt Chain A Binding Site BS01

Receptor Information
>4ayt Chain A (length=564) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNP
TVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFS
SILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVG
ISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQL
AEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATG
LSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYS
ELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPA
RPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISL
DGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI
QRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPK
ILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAV
LDQGKITEYGKHEE
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain4ayt Chain A Residue 1717 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ayt Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Resolution2.85 Å
Binding residue
(original residue number in PDB)		R170 Y234
Binding residue
(residue number reindexed from 1)		R17 Y81
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ayt, PDBe:4ayt, PDBj:4ayt
PDBsum4ayt
PubMed23716676
UniProtQ9NRK6|ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial (Gene Name=ABCB10)

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