Structure of PDB 4av1 Chain A Binding Site BS01

Receptor Information
>4av1 Chain A (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFS
CFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4av1 The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks
Resolution3.1 Å
Binding residue
(original residue number in PDB)		S16 R18 K22 R34 W51
Binding residue
(residue number reindexed from 1)		S11 R13 K17 R29 W46
Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

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Molecular Function
External links
PDB RCSB:4av1, PDBe:4av1, PDBj:4av1
PDBsum4av1
PubMed22683995
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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