Structure of PDB 4ar8 Chain A Binding Site BS01

Receptor Information
>4ar8 Chain A (length=391) Species: 1513 (Clostridium tetani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DINKLIEEGKKHYLPKTYTFDNGKIIIKAGDKVEESKIQKLYWASKEVKS
QFHRIIGNDKPLEVGNADDILTIVIYNNPEEYKLNKTLYGYSVDNGGIYI
EGIGTFFTYERTPQESIYSLEELFRHEFTHYLQGRYLIPGLFNKGDFYKG
NNGRITWFEEGSAEFFAGSTRTSVLPRKSMVGGLSKNPKERFNADKLLHS
KYSDGWDFYKYGYAFSDYMYNNNKKLFSDLVSTMKNNDVKGYEALIEESS
KDSKINKDYEYHMENLVNNYDNYTIPLVSDDYMKQYDNKSLHEIKSDIEK
AMDVKNSQITKESSQYFDTYNLKATYTLSSNKGEISNWNYMNNKINEALN
KLDNLSWGGYKTVTAYFSNPRLNSNNEVVYDIVFHGLLSHN
Ligand information
Receptor-Ligand Complex Structure
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PDB4ar8 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		G435 G436 S455 Y457 H465 E466 H469 E499 Y541 W545 Y548
Binding residue
(residue number reindexed from 1)		G96 G97 S116 Y118 H126 E127 H130 E160 Y202 W206 Y209
Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ar8, PDBe:4ar8, PDBj:4ar8
PDBsum4ar8
PubMed23703618
UniProtQ899Y1|COLT_CLOTE Collagenase ColT (Gene Name=colT)

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