Structure of PDB 4aim Chain A Binding Site BS01

Receptor Information
>4aim Chain A (length=698) Species: 190650 (Caulobacter vibrioides CB15) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPMFDIKRKTIEWGGKTLVLETGRIARQADGAVLATMGETVVLATAVFAK
SQKPGQDFFPLTVNYQEKTFAAGKIPGGFFKREGRPSEKETLVSRLIDRP
IRPLFVKGFKNEVQVVVTVLQHDLENDPDILGMVAASAALCLSGAPFMGP
IGAARVGWVDGAYVLNPTLDEMKESKMDLVVAGTADAVMMVESEIQELSE
EIVLGGVNFAHQQMQAVIDAIIDLAEHAAKEPFAFEPEDTDAIKAKMKDL
VGADIAAAYKIQKKQDRYEAVGAAKKKAIAALGLSDENPTGYDPLKLGAI
FKELEADVVRRGILDTGLRIDGRDVKTVRPILGEVGILPRTHGSALFTRG
ETQAIVVATLGTGDDEQFIDALEGTYKESFLLHYNFPPYSVGETGRMGSP
GRREIGHGKLAWRALRPMLPTKEDFPYTIRLVSEITESNGSSSMATVCGS
SLAMMDAGVPLVRPVSGIAMGLILEQDGFAVLSDILGDEDHLGDMDFKVA
GTSEGLTSLQMDIKIAGITPAIMEQALAQAKEGRAHILGEMNKAMDAPRA
DVGDFAPKIETINIPTDKIREVIGSGGKVIREIVATTGAKVDINDDGVVK
VSASDGAKIKAAIDWIKSITDEAEIGKIYDGKVVKVVDFGAFVNFFGAKD
GLVHVSQISNERVAKPSDVLKEGQMVKVKLLGFDDRGKTKLSMKVVDQ
Ligand information
Receptor-Ligand Complex Structure
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PDB4aim Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		V104 G142 P144 G147 A223 E224 A226 A227 P230 F231
Binding residue
(residue number reindexed from 1)		V106 G144 P146 G149 A225 E226 A228 A229 P232 F233
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4aim, PDBe:4aim, PDBj:4aim
PDBsum4aim
PubMed22724061
UniProtQ9AC32|PNP_CAUVC Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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